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脑蛋白44抗体价格

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  • 南京森贝伽生物科技有限公司
  • 2014-02-27 16:54:38
  • 南京市
  • 南京
  • 1907

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【简单介绍】

脑蛋白44抗体由南京森贝伽长期现货供应,产品种类齐全。公司生产的抗体每个流程都执行严格的检测标准,我们将为您提供高品质的抗体,咨询。

【详细说明】

脑蛋白44抗体产品质量有保证,公司生产的每一个抗体都经过严格检测和稳定性测试,保证了结果的准确性、敏感性、特异性。南京森贝伽生物科技有限公司为服务更多科研工作者的需要公司现经营脑蛋白44抗体ELISA试剂盒、标准品、染色液、染色试剂盒、培养基等多种科研产品。公司产品质量有保证、*,为广大客户提供完善的售前、售中、售后服务,公司生产的产品也已获得广大客户的信赖。如有任何疑问,我们将竭诚为您服务!
英文名称 BRP44
中文名称 脑蛋白44抗体
别    名 ESTM43; MGC125753; BR44_HUMAN; Brain protein 44; BRP44; DKFZp564B167; MGC125752; rCG_46381; RGD1563422; RP1-295C6.1.
说 明 书 0.2ml  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human BRP44
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
脑蛋白44抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
脑蛋白44抗体产品介绍 background:
BRP44 is a 127 amino acid protein belonging to the UPF0041 family. The gene that encodes BRP44 maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
Mediates the uptake of pyruvate into mitochondria.

Subunit:
The functional 150 kDa pyruvate import complex is a heteromer of MPC1 and MPC2 (By similarity).

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.

Similarity:
Belongs to the mitochondrial pyruvate carrier (MPC) family.

Database links:
UniProtKB/Swiss-Prot: O95563.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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