美国NovaBios
疟疾抗原（PLDH）疟疾抗原检测试剂盒（PLDH）
广州健仑生物科技有限公司
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恶性疟原虫、间日疟原虫、三日疟原虫、卵形疟原虫检测试剂盒
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美国NovaBios疟疾抗原（PLDH）疟疾抗原检测试剂盒（PLDH）
检查
1.血象
红细胞和血红蛋白在多次发作后下降，恶性疟尤重；白细胞总数初发时可稍增，后正常或稍低，白细胞分类单核细胞常增多，并见吞噬有疟色素颗粒。
2.疟原虫检查
血液涂片（薄片或厚片）染色查疟原虫。并可鉴别疟原虫种类。骨髓涂片染色查疟原虫，阳性率较血片高。
3.血清学检查
抗疟抗体一般在感染后2～3周出现，4～8周达高峰，以后逐渐下降。现已应用的有间接免疫荧光、间接血凝与酶联免疫吸附试验等，阳性率可达90%。一般用于流行病学检查。
诊断
1.流行病学
有在疟疾流行区居住或旅行史，近年有疟疾发作史或近期曾接受过输血的发热患者都应被怀疑。
2.临床表现
典型的周期性寒战、发热、出汗可初步诊断。不规律发热，而伴脾、肝大及贫血，应想到疟疾的可能。凶险型多发生在流行期中，多急起，高热寒战，昏迷与抽搐等。流行区婴幼儿突然高热、寒战、昏迷，也应考虑本病。
3.实验室检查
主要是查找疟原虫，通常找到即可确诊。血片找疟原虫应当在寒战发作时采血，此时原虫数多、易找。需要时应多次重复查找。并一定要做厚血片寻找。如临床高度怀疑而血片多次阴性可做骨髓穿刺涂片查找疟原虫。
4.分子生物学技术诊断法
（1）聚合酶链反应（PCR）检测检测的灵敏性和特异性均较高。PCR检测方法已在原来的基础上发展成多种方法，如巢式PCR、反转录酶PCR、PCR-ELISA等。除可以直接检测血样中的疟原虫外，还可以检测滤纸干血滴上的疟原虫。已从检测恶性疟原虫发展到检测间日疟原虫。
（2）DNA探针检测DNA探针检测具有良好的特异性和稳定性。
5.治疗性诊断
临床表现很象疟疾，但经多次检查未找到疟原虫。可试用杀灭红内期原虫的药物（如氯喹），治疗48小时发热控制者，可能为疟疾。但注意耐氯喹虫株。
美国NovaBios疟疾抗原（PLDH）疟疾抗原检测试剂盒（PLDH）
an examination
Blood
Erythrocytes and hemoglobin decreased after multiple episodes, falciparum malaria; the total number of white blood cells can be slightly increased, after normal or slightly lower, white blood cell classification of mononuclear cells often increased, and see phagocytosis of malaria particles.
2. Plasmodium
Blood smear (flakes or thick slices) stained against malaria parasites. And identify malaria parasite species. Bone marrow smear on the detection of malaria parasite, the positive rate higher than the blood tablets.
3. serological examination
Antimalarial antibodies generally occur 2 to 3 weeks after infection, 4 to 8 weeks to reach the peak, then gradually decreased. Has been applied with indirect immunofluorescence, indirect hemagglutination and enzyme-linked immunosorbent assay, the positive rate of up to 90%. Generally used for epidemiological examination.
diagnosis
Epidemiology
There is a history of living or traveling in a malaria endemic area, a recent history of malaria or a fever who has recently received a blood transfusion should be suspected.
2. Clinical manifestations
Typical periodic chills, fever, sweating can be a preliminary diagnosis. Irregular fever, and with spleen, liver and anemia, should think of the possibility of malaria. Dangerous type occurred in the popular period, more anxious, high fever chills, coma and convulsions and so on. Epidemic area infants and young children suddenly fever, chills, coma, should also consider the disease.
3. Laboratory check
Mainly to find malaria parasites, usually found to be diagnosed. Blood tablets to find malaria parasites should be in the chills when the blood, this time the number of protozoa, easy to find. If necessary, repeat the search. And must do thick blood tablets to find. Such as clinical suspicion and the number of negative blood can do bone marrow puncture smear to find malaria parasites.
4. Molecular biology technology diagnostic method
(1) Polymerase chain reaction (PCR) detection of the sensitivity and specificity were higher. PCR detection method has been developed on the basis of the original method, such as nested PCR, reverse transcriptase PCR, PCR-ELISA and so on. In addition to direct detection of blood samples in the malaria parasite, but also can be detected on the filter dry blood drops of malaria parasites. Has been developed from the detection of Plasmodium falciparum to the detection of Plasmodium vivax.
(2) DNA probe detection DNA probe detection has good specificity and stability.
5. Therapeutic diagnosis
Clinical manifestations like malaria, but after repeated check not found malaria parasite. Can try to kill red protozoa drugs (such as chloroquine), the treatment of 48 hours of fever control, may be malaria. But pay attention to chlor-resistant quinta strains.
美国NovaBios疟疾抗原（PLDH）
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【公司名称】 广州健仑生物科技有限公司
【市场部】 杨永汉
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【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室
