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小鼠抗血管内皮生长因子A抗体

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  • 公司名称上海泛柯实业有限公司
  • 品       牌
  • 型       号
  • 所  在  地上海
  • 厂商性质经销商
  • 更新时间2015/5/6 13:55:35
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小鼠抗血管内皮生长因子A抗体产品介绍:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
小鼠抗血管内皮生长因子A抗体 产品信息
英文名称VEGF-A
中文名称小鼠抗血管内皮生长因子A抗体
别    名Vascuoar endothelial growth factor A; vascular endothelial growth factor A isoform 2 precursor; Vegf; VEGF164; VEGFA; MGC70609; MVCD1; VEGF; VPF.
说 明 书0.1ml  0.2ml  
研究领域肿瘤  免疫学  生长因子和激素  血管内皮细胞  
抗体来源Mouse
克隆类型Monoclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, Guinea Pig, 
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量40-45kDa
性    状Lyophilized or Liquid
浓    度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human VEGF-A
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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