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广州健仑生物科技有限公司

广州健仑长期供应各种生物原料，主要代理品牌：西班牙Certest。

主要产品包括各种生物单克隆抗原抗体、重组蛋白。

西班牙Certest溶血性A链球菌抗体

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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癌症，虽然总是带着危险的，但真正对生命造成威胁的是当癌细胞开始扩散到不同的领域和遍及全身时。现在，美国密苏里大学(MU)的研究人员发现，由细菌用作通讯系统的一个分子可以被操纵来阻止癌细胞扩散。MU兽医医学院比较肿瘤学和表观遗传学实验室的助理研究教授和副主任Senthil Kumar说，这个通讯系统可用于“告诉”癌细胞如何行动，甚至是死亡的命令。
“在感染期间，细菌会释放出分子，使得它们能够彼此‘交谈’，” Kumar说，他了这项研究。“所述信号根据释放分子的类型，告诉其他细菌繁殖，逃避免疫系统甚至停止蔓延。我们发现，如果我们将‘停止蔓延’的细菌分子引入癌细胞中，这些细胞不但会停止扩散，而且它们也将会开始死亡。”
这项研究发表于《PLoS ONE》杂志上，Kumar，以及合著者、MU兽医医学院的副教授杰弗里·布莱恩，使用称为ODDHSL的细菌通讯分子用来治疗在培养基中生长的人胰腺癌细胞。经过治疗后，人胰腺癌细胞停止繁殖，未能迁移并开始死亡。
“我们之所以使用胰腺癌细胞，是因为这些细胞是发生在人体内zui强大的，侵袭性的以及难以杀灭的癌细胞，” Kumar说。“为了表明，这种分子不仅可以阻止癌细胞扩散，而且实际上也会导致它们死亡，这是非常令人兴奋的。因为这个治疗方法表明，其很有希望应用于像胰腺癌这种侵袭性的癌症。我们相信它也可用于其他类型的癌细胞，以及我们实验室正在其他类型的癌细胞中测试该治疗方法。”
Kumar说，他研究的下一步是在动物和人体试验发生前，寻找一个更有效的方式将该分子引入癌细胞中。
“现在，我们zui大的挑战是，寻找一种有效的方式引入该分子，” Kumar说。“在这个时候，我们只能够用这种分子在实验室中治疗癌细胞。现在，我们使用一个更好的方法来处理动物癌症，看看这个治疗是否真的有效。本研究的早期结果是有希望的。如果进一步的研究，包括动物实验，都成功后，下一步是将这个方法应用于临床试验。”
预后良好的患者可幸免进行带有严重副作用的侵入性治疗，但不对侵入性肿瘤进行侵入治疗或可导致死亡。癌症之所以致命，在很大程度上是由于其发生了转移，从一个器官或组织转移到另一个器官或组织。癌症致死绝大多数与转移有关。
对于抗原抗体癌来说，被称为“上皮间质转化”的过程助推了这种转移。上皮细胞系附着在与环境接触的皮肤和胃肠道中。间质细胞是胚胎组织和结缔组织中的一种细胞类型，其在那里形成非常松散的。肿瘤细胞失去成熟上皮细胞的特性(如附着于环境的能力)，获得间质细胞的能力，使其能够轻松地在细胞间流动并进入血液，从而迁移到远处的器官和组织。

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【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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【腾讯  】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

Cancer, while always dangerous, is a real threat to life as cancer cells begin to spread to different areas and spread throughout the body. Now researchers at the University of Missouri (MU) find that a molecule that bacteria use as a communication system can be manipulated to stop cancer cells from spreading. Senthil Kumar, professor and deputy director of assistant research at the MU Veterinary Medical School's Comparative Oncology and Epigenetics Laboratory, said the communication system can be used to "l" how cancerous cells act or even die.
"During infection, bacteria release molecules so they can talk to each other," Kumar said, who led the study. "The signal ls other bacteria to breed, escape the immune system, or even stop spreading, depending on the type of molecule released, and we found that if we introduce 'stop-going' bacterial molecules into cancer cells, they not only stop spreading, but they also It will start to die. "
The study, published in PLoS ONE, by Kumar and co-author Jeffrey Bryan, an associate professor at MU Veterinary Medical School, uses a bacterial communication molecule called ODDHSL to treat human pancreas that grows in culture cancer cell. After treatment, human pancreatic cancer cells stop multiplying, fail to migrate and begin to die.
"The reason we use pancreatic cancer is because these cells are the most powerful, aggressive and hard-to-kill cancer in the body," Kumar said. "It's very exciting to show that this molecule not only stops the spread of cancer cells but actually causes them to die, as this treatment shows promise for promising invasiveness like pancreatic cancer We believe it is also available for other types of cancer cells and our laboratory is testing the treatment in other types of cancer cells. "
Kumar said the next step in his research is to find a more effective way to introduce the molecule into cancer cells before animal and human trials occur.
"Now, our biggest challenge is to find an effective way to introduce that molecule," Kumar said. "At this point, we were only able to use this molecule to treat cancer cells in the laboratory, and now we use a better approach to treating animal cancers and see if the treatment is really effective. The early results of this study were Hopefully, if further research, including animal experiments, is successful, the next step is to apply the method to clinical trials. "
Patients with good prognosis can be spared aggressive treatment with serious side effects, but not invasive treatment of invasive tumors or can lead to death. The cancer is fatal, in large part because of its metastasis, its transfer from one organ or tissue to another organ or tissue. The vast majority of cancer death and metastasis.
For antigen-antibody cancers, a process called "epithelial mesenchymal transition" helps to promote this metastasis. Epithelial cell lines attach to the environment in contact with the skin and gastrointestinal tract. Stromal cells are a type of cell in embryonic tissue and connective tissue where they form a very loose connection. Tumor cells lose the characteristics of mature epithelial cells (e.g., attached to the capacity of the environment), the ability of mesenchymal cells obtained between, it can easily flow between the cells and into the bloodstream, so migrated to distant organs and tissues.