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Anti-Phospho-CHK2(Thr68),磷酸化细胞周期检测点激酶2抗体科研

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更新时间:2018-04-11 23:45:43浏览次数:318次

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“Anti-Phospho-CHK2(Thr68),磷酸化细胞周期检测点激酶2抗体科研“我公司拥有*的细胞服务技术,*的仪器设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等,广泛用于多种分析研究与技术测定。咨询,我们将竭诚为你服务!

详细介绍

Anti-Phospho-CHK2(Thr68),磷酸化细胞周期检测点激酶2抗体科研产品介绍:

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene.


与“Anti-Phospho-CHK2(Thr68),磷酸化细胞周期检测点激酶2抗体科研"有关的产品:

Anti-HCV-NS3  丙型肝炎病毒-NS3抗体
Anti-HCV-NS4a  丙型肝炎病毒-NS4a抗体
Anti-CD36L1/SRB1(Scavenger Receptor Class B Type 1)  高密度脂蛋白受体/清道夫受体抗体
Anti-Heamachrome  血红素抗体
Anti-c-erbB2(HER2 receptor)  抗HER2受体抗体
Anti-HER2 receptor(erbB-2 isoform 2)  抗c-erbB-2受体抗体
Anti-HER2 receptor(NT)(erbB-2 isoform 2 receptor N-Terminus)  抗c-erbB-2受体抗体(N端)
Anti-HER2 receptor(NT)(erbB-2 isoform 2 receptor N-Terminus)  抗c-erbB-2受体抗体(N端)
Anti-HEV  戊型肝炎病毒抗体
Anti-HGF(hepatocyte growth factor)  肝细胞生长因子抗体

Anti-Phospho-CHK2(Thr68),磷酸化细胞周期检测点激酶2抗体科研产品详情:
产品编号:HRK-3721R
产品规格: 0.1ml/0.2ml
产品别名:bA444G7; CHK2 checkpoint homolog; CHK2_HUMAN; Serine/threonine-protein kinase Chk2; CDS 1; CDS1; Checkpoint kinase 2; Checkpoint like protein CHK2; Chek 2; Chek2; Chk 2; CHK2 checkpoint homolog (S. pombe); CHK2 checkpoint homolog; HuCds 1; HuCds1; LFS 2; LFS2; PP1425; RAD 53; RAD53; Rad53 homolog; Serine/threonine protein kinase Chk2
产品价格:询价(电询或客服)
产品用途:科研实验
贮 存:   贮存于-20℃.

与“Anti-Phospho-CHK2(Thr68),磷酸化细胞周期检测点激酶2抗体科研"有关的其他产品:

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河豚毒素抗体 Anti-TTX
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