Anti-phospho-BCAR1(Tyr410),磷酸化乳腺癌抗雌激素耐药蛋白1抗体科研产品介绍：
p130 represents one of several known substrates for v-Crk encoded p47. p130 Cas (for Crk-associated substrate) exhibits a high level of tyrosine phosphorylation and is tightly associated with v-Crk, suggesting a role in v-Crk-mediated cell signaling. The molecular cloning of p130 Cas has shown it to represent a novel SH3 containing signaling molecule with a cluster of multiple putative SH2-binding motifs for v-Crk. By immunoprecipitation analysis, p130 Cas has been shown to be highly phosphorylated at tyrosine residues subsequent to either v-Src p60 or v-Crk-mediated transformation and to form stable complexes with both of these transforming proteins. p130 Cas behaves as an extremely potent substrate for protein tyrosine kinases and has been reported to relocate from the cytoplasm to cell membrane upon tyrosine phosphorylation. One proposed model is that the SH2 domain of v-Crk functions to activate c-Src kinase, which in turn phosphorylates p130 Cas.
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Anti-phospho-BCAR1(Tyr410),磷酸化乳腺癌抗雌激素耐药蛋白1抗体科研产品详情：
产品编号：HRK-6224R
产品规格: 0.1ml/0.2ml
产品别名：BCAR1 (phospho Y410); BCAR1(phospho Y410); p-BCAR1(p-Tyr410); Breast cancer anti estrogen resistance 1 protein; BCAR 1; Bcar1; BCAR1_HUMAN; Breast cancer anti estrogen resistance 1; Breast cancer anti-estrogen resistance protein 1; CAS; Cas scaffolding protein family member 1; Crk associated substrate; Crk associated substrate p130Cas; CRK-associated substrate; CRKAS; P130CAS
产品价格：询价(电询或客服)
产品用途：科研实验
贮 存： 贮存于-20℃.
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