本公司，是专业经营生物试剂，抗体，细胞，标准品，对照品的公司，在广大用户的帮助和支持下，经过不懈的努力，已成为国内生命科学领域产品的主要供应商之一，代理许多*水平的高科技产品，包括分子生物学、细胞生物学、免疫学、诊断等多个研究及应用领域。公司的服务和业务网络遍及全国，在同行获得*好评。
Anti-RIM2抗体,神经元突触膜胞外分泌调节蛋白2抗体*简单介绍：
产品别名：Non small cell lung cancer RimL3a protein; Rab3 interacting molecule 2; RAB3IP3; Regulating synaptic membrane exocytosis protein 2; Rims2; RIMS2_HUMAN.
产品用途：科研实验
产品编号：BYK-11357R
性 状：Lyophilized or Liquid
浓 度：1mg/1ml
亚 型：IgG
贮 存：贮存于-20℃.
此抗体本公司有单抗和多抗，可用于免疫组化（IHC），免疫印迹（WB），酶联免疫(ELISA)，IF、IP、流式细胞术等实验（可来电索取说明）
相关标记有：Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记
Anti-RIM2抗体,神经元突触膜胞外分泌调节蛋白2抗体*产品说明：Rab3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis (1-2). Rab3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (rab3 interacting molecule), a putative effector protein for Rab3s, is composed of an amino-terminal zinc-finger motif and carboxy-terminal PDZ and C2 domains. Rim exists as two variants, Rim1 and Rim2, produced by alternative splicing (3). Rim1 is expressed near the active zone at the synapse, where it interacts in a GTP-dependent manner with Rab3, located on synaptic vesicles (4). Therefore, Rim serves as a Rab3-dependent regulator of synaptic-vesicle fusion by forming a GTP-dependent complex between synaptic plasma membranes and docked synaptic vesicles (5). Both Rim1 and Rim2 can bind to cAMP-GEFII, which is a direct target of cAMP in regulated exocytosis and is responsible for cAMP-dependent, PKA-dependent exocytosis (3). Rim also localizes on the plasma membrane of INS-1E cells and pancreatic beta-cells. Rab3 binding domain of Rim enhances glucose-stimulated secretion in intact cells and Ca2+-stimulated exocytosis in permeabilized cells, suggesting that Rim may also play a regulatory role in insulin secretion (6).
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
连续使用时4°C存储，保质期六个月补体C1qα链多肽抗体*存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。
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