上海博研生物为您提供：Anti-Smoothened/SMO,膜蛋白Smoothened抗体说明书
Rabbit Anti-Smoothened/SMO antibody
Catalog Number : BYK- 2801R
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: Smoothened （SMOH）, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein （PTCH） to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas.
SMO expression has been documented in bladder, blood, brain, the central nervous system, skin, and ureter. ESTs have been isolated from amnion, bone, brain, breast, embryo, eye, heart, nerve, and skin libraries.
Specificity :
– Anti- Smoothened/SMO is a rabbit polyclonal antibody unconjugated
– specific for Smoothened/SMO of hu,mo, rat, Rb, pig
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt: 86kDa
Anti-Smoothened/SMO,膜蛋白Smoothened抗体说明书Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– IHC-P=1:100-500 IHC-F=1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Anti-Smoothened/SMO,膜蛋白Smoothened抗体说明书Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
