艾美捷磷酸化-Tau（Thr 231）抗体中英文说明书

磷酸化-Tau抗体（Thr231）仅在苏-氨酸231磷酸化时检测Tau的内源性水平。

艾美捷磷酸化-Tau（Thr 231）抗体#GBS-ITA0919-100u抗体：

中文名称：Immunotag™ Phospho-Tau (Thr231) 抗体

英文名字：Immunotag™ Phospho-Tau (Thr231) Antibody

G-Biosciences 编号：GBS-ITA0919-100u

磷酸化-Tau（Thr 231）抗体物化性质：

目标蛋白 磷酸Tau（Thr231）

克隆性 多克隆

储存/稳定性 -20°C/1 年

应用 WB，酶联免疫吸附法

推荐稀释度 WB 1：500-1：2000

浓度 1毫克/毫升

反应性物质 人，老鼠，大鼠

寄主物种 兔

免疫原 一种衍生自人Tau的合成肽，围绕苏-氨酸231的磷酸化位点

特 异性 磷酸化-Tau抗体（Thr231）仅在苏-氨酸231磷酸化时检测Tau的内源性水平

纯化 该抗体来自纯化的兔血清，通过磷酸化和非磷酸肽亲和柱上的顺序色谱进行亲和纯化。

形式 兔IgG在磷酸盐缓冲盐水中，pH 7.4，150mM NaCl，0.02%叠-氮-化钠和50%甘油。储存在-20°C.自收到之日起可稳定保存12个月

基因名称 马普特

藏品编号 P10636

细胞通路/类别 一抗多克隆抗体

蛋白质分子量 78kDa

用法 仅供研究使用！不适用于诊断或治疗程序

Target Protein Phospho-Tau (Thr231)

Clonality Polyclonal

Storage/Stability -20°C/1 year

Application WB,ELISA

Recommended Dilution WB 1:500-1:2000

Concentration 1 mg/ml

Reactive Species Human,Mouse,Rat

Host Species Rabbit

Immunogen A synthesized peptide derived from human Tau around the phosphorylation site of Threonine 231

Specificity Phospho-Tau (Thr231) Antibody detects endogenous levels of Tau only when phosphorylated at Threonine 231

Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Form Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

Gene Name MAPT

Accession No. P10636

Alternate Names AI413597; AW045860; DDPAC; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; MAPT; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Microtubule-associated protein tau; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; Paired helical filament-tau; PHF tau; PHF-tau; PPND; PPP1R103; Protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; TAU; TAU_HUMAN; Tauopathy and respiratory failure, included;

Description Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Cell Pathway/ Category Primary Polyclonal Antibody

Protein MW 78kDa

Usage For Research Use Only! Not for diagnostic or therapeutic procedures.