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检测Anti-PGA1/AIRE抗体,免疫调节蛋白AIRE抗体,可用于免疫组化(IHC),免疫印迹(WB),酶联免疫(ELISA),IF、IP、流式细胞术等实验(可来电索取说明)!!
本公司,是专业经营生物试剂,抗体,细胞,标准品,对照品的公司,在广大用户的帮助和支持下,经过不懈的努力,已成为国内生命科学领域产品的主要供应商之一,代理许多*水平的高科技产品,包括分子生物学、细胞生物学、免疫学、诊断等多个研究及应用领域。公司的服务和业务网络遍及全国,在同行获得*好评。
检测Anti-PGA1/AIRE抗体,免疫调节蛋白AIRE抗体简单介绍:
产品别名:AIRE-1; AIRE; AIRE_HUMAN; AIRE1; APECED; APECED protein; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; Autoimmune regulator; Autoimmune regulator protein; PGA1.
产品用途:科研实验
产品编号:BYK-12453R
性 状:Lyophilized or Liquid
浓 度:1mg/1ml
亚 型:IgG
贮 存:贮存于-20℃.
此抗体本公司有单抗和多抗,可用于免疫组化(IHC),免疫印迹(WB),酶联免疫(ELISA),IF、IP、流式细胞术等实验(可来电索取说明)
相关标记有:Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记
检测Anti-PGA1/AIRE抗体,免疫调节蛋白AIRE抗体产品说明:The autoimmune regulator gene, which is defective in the hereditary auto-immune disease APECED, encodes the transcriptional activator AIRE. AIRE is expressed in the medullary epithelial cells and monocyte-dendritic cells of the thymus, with lower expression in the spleen, fetal liver and lymph nodes. In adult tissue, AIRE expression in the thymus is confined to the medulla and the cortico-medullary junction, where it is modulated by thymocytes undergoing negative selection. At the cellular level, AIRE is located in microtubular structures of the cyto-skeleton and in discrete nuclear dots resembling ND10 nuclear bodies. AIRE is induced by developing early thymocytes and is associated with the correct establishment of a regular thymic environment. AIRE regulates thymic architecture via transcriptional control of downstream target genes. AIRE mutations in APECED patients may affect thymic T cell selection and the formation of self-tolerance.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
连续使用时4°C存储,保质期六个月补体C1qα链多肽抗体*存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。
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