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检测Anti-APC11抗体,细胞周期后期促进蛋白亚基11抗体

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产品简介

检测Anti-APC11抗体,细胞周期后期促进蛋白亚基11抗体,可用于免疫组化(IHC),免疫印迹(WB),酶联免疫(ELISA),IF、IP、流式细胞术等实验(可来电索取说明)!!

详细介绍

本公司,是专业经营生物试剂,抗体,细胞,标准品,对照品的公司,在广大用户的帮助和支持下,经过不懈的努力,已成为国内生命科学领域产品的主要供应商之一,代理许多*水平的高科技产品,包括分子生物学、细胞生物学、免疫学、诊断等多个研究及应用领域。公司的服务和业务网络遍及全国,在同行获得*好评。

检测Anti-APC11抗体,细胞周期后期促进蛋白亚基11抗体简单介绍:

产品别名:ANAPC 11; ANAPC11; Anaphase promoting complex subunit 11; Anaphase promoting complex subunit 11 homolog (yeast); Anaphase promoting complex subunit 11 homolog; Anaphase-promoting complex subunit 11; Apc 11; Apc 11p; APC11 anaphase promoting complex subunit 11 homolog (yeast); APC11 anaphase promoting complex subunit 11 homolog; APC11; APC11_HUMAN; Apc11p; Cyclosome subunit 11; Hepatocellular carcinoma associated RING finger protein; Hepatocellular carcinoma-associated RING finger protein; HSPC 214; HSPC214; MGC882; Yeast APC 11 homolog; Yeast APC11 homolog.

产品用途:科研实验

产品编号:BYK-12484R

性 状:Lyophilized or Liquid

浓 度:1mg/1ml

亚 型:IgG

贮 存:贮存于-20℃.

此抗体本公司有单抗和多抗,可用于免疫组化(IHC),免疫印迹(WB),酶联免疫(ELISA),IF、IP、流式细胞术等实验(可来电索取说明)

相关标记有:Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记

检测Anti-APC11抗体,细胞周期后期促进蛋白亚基11抗体产品说明:Comprising more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to APC and activates APC’s cyclin-ubiquitination activity. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC; thus preventing APC activation. APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2). In addition, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1.

保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
连续使用时4°C存储,保质期六个月补体C1qα链多肽抗体*存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。

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