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Anti-LIV-1/SLC39A6抗体,雌激素调节蛋白LIV1/锌转运蛋白抗体

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更新时间:2018-02-06 10:31:05浏览次数:447次

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产品简介

Anti-LIV-1/SLC39A6抗体,雌激素调节蛋白LIV1/锌转运蛋白抗体,此抗体本公司有单抗和多抗,可用于免疫组化(IHC),免疫印迹(WB),酶联免疫(ELISA),IF、IP、流式细胞术等实验(可来电索取说明)!!

详细介绍

本公司,是专业经营生物试剂,抗体,细胞,标准品,对照品的公司,在广大用户的帮助和支持下,经过不懈的努力,已成为国内生命科学领域产品的主要供应商之一,代理许多*水平的高科技产品,包括分子生物学、细胞生物学、免疫学、诊断等多个研究及应用领域。公司的服务和业务网络遍及全国,在同行获得*好评。

Anti-LIV-1/SLC39A6抗体,雌激素调节蛋白LIV1/锌转运蛋白抗体简单介绍:

产品别名:LIV1; LIV 1; LIV-1; solute carrier family 39, member 6; solute carrier family 39 (zinc transporter), member 6 isoform 1; Zinc transporter ZIP6; Zrt- and Irt-like protein 6; ZIP-6; Endoplasmic reticulum membrane-linked protein; Ermelin; S39A6_HUMAN.

产品用途:科研实验

产品编号:BYK-1895R

性 状:Lyophilized or Liquid

浓 度:1mg/1ml

亚 型:IgG

贮 存:贮存于-20℃.

此抗体本公司有单抗和多抗,可用于免疫组化(IHC),免疫印迹(WB),酶联免疫(ELISA),IF、IP、流式细胞术等实验(可来电索取说明)

相关标记有:Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记

Anti-LIV-1/SLC39A6抗体,雌激素调节蛋白LIV1/锌转运蛋白抗体产品说明:LIV-1 is expressed as two isoforms. LIV-1 is a multi-pass cell membrane protein that is 749 amino acids in length and is expressed abundantly in breast, prostate, placenta, kidney, pituitary and corpus callosum, as well as in cells derived from various types of cancers affecting the glands, cervix and lungs. LIV-1 is a member of the ZIP transporter protein family which consists of 14 members that transport zinc. LIV-1 transports zinc from its position on the plasma membrane into the cytosol of the cell and contains a histidine-rich transmembrane domain which is thought to bind zinc and aid in its transportation. LIV-1 is thought to be important for zinc uptake in neuroblastoma cells and may also be crucial for maintaining zinc homeostasis, a process which aids in the prevention of cancer and disease. Activated estrogen receptors are thought to regulate LIV-1 expression at the level of transcription, via the mRNA precursor to LIV-1 which associates with estrogen receptors that are activated by growth factors and estradiol. LIV-1 is upregulated in hormone-rich tissue, including breast and cervical cancer, where it is thought to affect cell motility and may play an important role in tumor development and metastasis. Conversely, less aggressive tumors may contain high levels of LIV-1 that could lead to apoptosis, indicating a dual role for LIV-1 in tumor suppression.

保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
连续使用时4°C存储,保质期六个月补体C1qα链多肽抗体*存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。

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