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博研生物现货提供“Anti-Androgen receptor抗体,雄激素受体抗体"，产品质量保证，提供，有任何质量问题可免费包退包换，咨询！
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【产品名称】：Anti-Androgen receptor抗体,雄激素受体抗体（实验）
【产品编号】：BYK-0118R
【产品规格】：0.1ml/0.2ml
【产品价格】：询价（电询或客服）
【抗体来源】：Rabbit OR Mouse or Goat
【产品用途】：科研实验，用于ELISA实验、免疫组化实验，WB实验，IF实验等，可，索取产品说明书！
【性 状】： Lyophilized or Liquid
【浓 度】： 1mg/1ml
【亚 型】： IgG
【贮 存】： 贮存于-20℃.
【相关标记】：HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【产品别名】：AIS; AIS; ANDR_HUMAN; Androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease); Androgen receptor; AR; DHTR; Dihydro Testosterone Receptor; Dihydrotestosterone receptor; HUMARA; HYSP1; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; Spinal and bulbar muscular atrophy; TFM.
【产品介绍】：The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
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