载脂蛋白L4抗体批发
『别名』APOL IV; ApoL-IV; APOL4; APOL4_HUMAN; Apolipoprotein L IV; Apolipoprotein L-IV; Apolipoprotein L4; APOLIV; CTA 212A2.2; OTTHUMP00000028937.
『浓度』1mg/1ml
『规格』0.2ml/200μg
『抗体来源』Rabbit
『克隆类型』polyclonal
『交叉反应』Human
『产品类型』一抗
『研究领域』心血管 细胞生物
『蛋白分子量』predicted molecular weight: 37kDa
『性状』Lyophilized or Liquid
『免疫原』KLH conjugated synthetic peptide derived from human APOL4/Apolipoprotein L4
『亚型』IgG
『纯化方法』affinity purified by Protein A
『储存液』Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
『产品应用』WB=1:100-500 ELISA=1:500-1000 载脂蛋白L4抗体批发 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
『保存条件』Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
『产品介绍』The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-IV (apolipoprotein L-IV), also known as APOL4, is a 351 amino acid protein that exists as multiple alternatively spliced isoforms, one of which is secreted. Expressed in spleen, placenta, spinal cord, uterus, testis and trachea, apoL-IV is thought to play a role in lipid exchange and transport throughout the body and may be involved in reverse cholesterol transport, specifically from peripheral cells to the liver. Overexpression of apoL-IV is associated with schizophrenia, suggesting that apoL-IV may play a role in the pathogenesis of neural disorders.
Function : May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Subcellular Location : Secreted.
Tissue Specificity : Widely expressed; the highest levels are in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis; levels are low in brain, heart and pancreas.
Similarity : Belongs to the apolipoprotein L family.
Database links : UniProtKB/Swiss-Prot: Q9BPW4.3
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