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小鼠抗促甲状腺素抗体

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更新时间:2018-05-15 13:40:32浏览次数:398次

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商铺产品:9811条

所在地区:上海上海

联系人:马经理 (销售专员)

产品简介

小鼠抗促甲状腺素抗体产品介绍:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

详细介绍

英文名称TSHB
中文名称小鼠抗促甲状腺素抗体
别    名CHNG4; Thyroid stimulating hormone beta subunit; Thyroid stimulating hormone, beta precursor; Thyrotropin beta subunit; TSHB; TSHB_HUMAN; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; Thyrotropin alfa.
说 明 书0.1ml  0.2ml  
研究领域免疫学  生长因子和激素  内分泌病  
抗体来源Mouse
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, 
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量15kDa
性    状Lyophilized or Liquid
浓    度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human TSHB
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
生 产 商BIOSS
PubMedPubMed
产品介绍background:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Function:
Indispensable for the control of thyroid structure and metabolism.

Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Subcellular Location:
Secreted.

Similarity:
Belongs to the glycoprotein hormones subunit beta family.

Gene ID:
7252


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