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阅读：689发布时间：2014-6-6
Rabbit Anti-Desmin抗体标记, FITC conjugated
FROM:ABCAM
Catalog Number : RS-91026R-FITC
Quantity size : 100ug(2mg/ml,Lyophilized. Buffer = 0.01M PBS, pH 7.4 with 10mg/ml BSA and 0.1% Sodium azide. Reconstitute with 100ul sterile distilled water. )
background:
filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures. Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function. Antidesmin antibodies are useful in identification of tumours of myogenic origin.
Function:
Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.
Specificity : · anti-Desmin is a rabbit Polyclonal antibody, FITC conjugated
· specific for anti-Desmin/FITC of Rat,mouse,hu.
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt：52 kDa
Application : · FCM: 1:20-100
· IF : 1:20-1:200 Desmin抗体标记
· Immunocytochemistry: 1:20-1:200
· Excitation spectrum: 490-495nm
· Emission spectrum: 520-530nm
· Optimal working dilutions must be determined by the end user.
· protect from light.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
商铺：https://www.afzhan.com/st132832/
主营产品：流式标记抗体，FITC,PE,CY3,5,7标记ELISA试剂盒、生化检测试剂盒、金标检测试剂盒、分子生物学试剂盒、进口国产胎牛血清、生物抗体、细胞，试剂耗材
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