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华瑞科研网-ELISA试剂盒
“Anti-C17orf42抗体,17号染色体开放阅读框42抗体科研“我公司拥有*的细胞服务技术,*的仪器设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等,广泛用于多种分析研究与技术测定。咨询,我们将竭诚为你服务!
Anti-C17orf42抗体,17号染色体开放阅读框42抗体科研产品介绍:
C17orf42 is a 360 amino acid protein that exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
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产品详情:
产品编号:HRK-9639R
产品规格: 0.1ml/0.2ml
产品别名:Chromosome 17 open reading frame 42; FLJ22729; Hypothetical protein LOC79736; MGC24674; UPF0629 protein C17orf42; TEFM_HUMAN
产品价格:询价(电询或客服)
产品用途:科研实验
贮 存: 贮存于-20℃.
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