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华瑞科研网-ELISA试剂盒
“Anti-CCDC40抗体,卷曲螺旋结构域蛋白40抗体科研“我公司拥有*的细胞服务技术,*的仪器设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等,广泛用于多种分析研究与技术测定。咨询,我们将竭诚为你服务!
Anti-CCDC40抗体,卷曲螺旋结构域蛋白40抗体科研产品介绍:
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.
Involvement in disease:
Defects in CCDC40 are the cause of primary ciliary dyskinesia type 15 (CILD15) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
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产品详情:
产品编号:HRK-8091R
产品规格: 0.1ml/0.2ml
产品别名:CCD40_HUMAN; ccdc 40; CCDC40; Coiled coil domain containing 40; coiled-coil domain containing 40; Coiled-coil domain-containing protein 40
产品价格:询价(电询或客服)
产品用途:科研实验
贮 存: 贮存于-20℃.
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