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华瑞科研网-ELISA试剂盒
华瑞科研网-ELISA试剂盒
“Anti-CDT2抗体,维甲酸调节核基质相关蛋白抗体科研“我公司拥有*的细胞服务技术，*的仪器设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等，广泛用于多种分析研究与技术测定。咨询，我们将竭诚为你服务！
Anti-CDT2抗体,维甲酸调节核基质相关蛋白抗体科研产品介绍：
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.
Tissue specificity: Expressed in placenta and testis, very low expression seen in skeletal muscle. Detected in all hematopoietic tissues examined, with highest expression in thymus and bone marrow. A low level detected in the spleen and lymph node, and barely detectable level in the peripheral leukocytes. RA treatment down-regulated the expression in NT2 cell.
与“Anti-CDT2抗体,维甲酸调节核基质相关蛋白抗体科研"有关的产品：
Anti-ILT2/CD85j(Immunoglobulin-like transcript 2) 细胞表面免疫球蛋白样转录因子2抗体
Anti-IRS P53 (Insulin receptor substrate P53) 胰岛素受体底物p53蛋白抗体
Anti-IRS-1 胰岛素受体底物-1抗体
Anti-IRS-2 胰岛素受体底物-2抗体
Anti-IRS-3 胰岛素受体底物-3抗体
Anti-IRS-4 胰岛素受体底物-4抗体
Anti-ISR（Insulin Receptor）（hu, cattle, mo, rat, horse, sheep, Rb, dog, chi） 胰岛素受体抗体
Anti-ISR-α （Insulin Receptor-α） 胰岛素受体-α抗体
Anti-ISR-β （Insulin Receptor-β） 胰岛素受体-β抗体
Anti-Integrin α4/CD49d(Integrin alpha 4) 整合素α4抗体
产品详情：
产品编号：HRK-7935R
产品规格: 0.1ml/0.2ml
产品别名：Lethal(2) denticleless protein homolog; CDW1; CDW1; DCAF2; DDB1 and CUL4 associated factor 2; Ddb1- and Cul4-associated factor 2; Denticleless homolog; Denticleless homolog (Drosophila); Denticleless protein homolog; Dtl; DTL_HUMAN; L2DTL; Lethal(2) denticleless protein homolog; RA regulated nuclear matrix associated protein; RAMP; Retinoic acid regulated nuclear matrix associated protein; Retinoic acid-regulated nuclear matrix-associated protein
产品价格：询价(电询或客服)
产品用途：科研实验
贮 存： 贮存于-20℃.
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环指蛋白148抗体 Anti-RNF148
钙磷蛋白2抗体 Anti-Calcyphosine 2/CAPS2
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