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Anti-phospho-BAD(Ser91),磷酸化相关死亡促进因子抗体科研

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更新时间:2018-05-13 10:47:06浏览次数:308次

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“Anti-phospho-BAD(Ser91),磷酸化相关死亡促进因子抗体科研"我公司拥有*的细胞服务技术,*的仪器设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等,广泛用于多种分析研究与技术测定。咨询,我们将竭诚为你服务!

详细介绍

Anti-phospho-BAD(Ser91),磷酸化相关死亡促进因子抗体科研产品介绍:

Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform. This antibody recognise the phosphorylation site of human Ser75, mouse Ser111, rat Ser112. 


与“Anti-phospho-BAD(Ser91),磷酸化相关死亡促进因子抗体科研"有关的产品:

Anti-CREB-1(cAMP responsive element binding protein-1)  环腺苷酸应答元件结合蛋白抗体
Anti-cRaf/Raf1(c-raf 1)  抗cRaf/Raf1抗体
Anti-phospho-CREB-1 (pSer133)   磷酸化环腺苷酸应答元件结合蛋白抗体
Anti-CRF/CRH (Corticotropin-Releasing Factor/hormone)  促肾上腺皮质激素释放因子
Anti-CRF/CRH (Corticotropin-Releasing Factor)  促肾上腺皮质激素释放因子抗体
Anti-CSIG(cellular senescence inhibited gene)  细胞衰老抑制基因抗体
Anti-Cripto-1(NT)  畸胎瘤衍化生长因子抗体(表皮生长因子相关肽)N端
Anti-Cripto-1(C-Terminus)  畸胎瘤衍化生长因子抗体(表皮生长因子相关肽)C端
Anti-CSMD1(CUB and Sushi muhiple domains1)  抑癌基因CSMD1抗体
Anti-CRTAM  CRTAM抗体

Anti-phospho-BAD(Ser91),磷酸化相关死亡促进因子抗体科研产品详情:
产品编号:HRK-12567R
产品规格: 0.1ml/0.2ml
产品别名:Bad (phospho S91); p-Bad (phospho S91); BBC 2; BBC2; BBC6; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl-2-like protein 8; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl2-L-8; BCL2L8; BclXL; Proapoptotic BH3 Only Protein
产品价格:询价(电询或客服)
产品用途:科研实验
贮 存:   贮存于-20℃.

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