G蛋白偶联受体42抗体*打折

暑期优惠*！G蛋白偶联受体42抗体*打折等各种科研实验抗体南京森贝伽公司长期专业供应公司抗体质量可靠，每一个抗体都经过严格检测和稳定性测试，保证了实验结果的准确性、敏感性、特异性。公司拥有国内的抗体服务技术、*的仪器设备和专业的技术人员，为您提供*的售前售后服务。森贝伽始终秉承产品“质量高、价格优、信誉好”为一体，不断努力为顾客提供更好更满意的产品，咨询订购G蛋白偶联受体42抗体*打折！
英文名称 FFAR3/GPR42
中文名称G蛋白偶联受体42抗体
别    名 FFA3R; Ffar3; FFAR3_HUMAN; Free fatty acid receptor 3; G protein coupled receptor 41; G-protein coupled receptor 41; gpcr41; GPR41; gpr42.
G蛋白偶联受体42抗体*打折
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  结合蛋白  G蛋白偶联受体  细胞骨架  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FFAR3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
G蛋白偶联受体42抗体*打折
产品介绍 background:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPRs translate extracellular signals into intracellular signals (a process called G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR41 (G-protein coupled receptor 41), also known as FFAR3 (Free fatty acid receptor 3), is a 346 amino acid multi-pass membrane protein that belongs to the G protein-coupled receptor family. Expressed at high levels in adipose tissue and at lower levels throughout the body, GPR41 functions as a receptor for short chain fatty acids via elevation of intracellular calcium levels and inhibition of adenylyl cyclase.

Function:
Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest level in adipose tissue, and lower expression across all tissues tested.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2865 Human

Omim: 603821 Human

SwissProt: O14843 Human

Unigene: 248055 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.