美国NOVABIOS-可替宁检测试剂盒-可替宁试剂盒-广州健仑生物科技有限公司

可替宁检测试剂盒

广州健仑生物科技有限公司

本司长期供应尼古丁（可替宁）检测试剂盒，其主要品牌包括美国NovaBios、广州健仑、广州创仑等进口产品，国产产品，试剂盒的实验方法是胶体金方法。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【包装规格】

1人份/袋，40人份/盒

【预期用途】

尼古丁(Nicotine)是烟草中的主要生物碱，是导致吸烟成瘾的物质动因，也是评价人体摄入烟草烟雾的常用指标。但因为尼古丁半衰期短，无法作为标志物检测，其代谢物可替宁因为半衰期长作为吸烟和戒烟的标志物。

本品采用竞争抑制法和胶体金免疫层析技术，用于快速定性检测人体唾液中的可替宁，适用于评价烟草烟雾摄入的初步筛查。

【主要组成成份】

可替宁检测试剂盒（40人份）：每人份铝箔袋单独包装。其中试剂盒由金标可替宁单克隆抗体、可替宁-BSA结合物、羊抗兔IgG多克隆抗体、硝酸纤维素膜、聚酯纤维素膜、塑料背衬、塑料模板组成。
一次性灭菌唾液取样棒（40人份）
唾液收集器（40人份）
使用说明书（1份）
【检验方法】
撕开铝箔袋，取出试剂，应在1小时内尽快使用。
拿出一次性唾液收集器。（步骤1）
手持收集器盖帽使海绵头含入口中，直至海绵头吸满液体（膨胀变软）。（步骤2）
将海绵头放回收集器并拧紧盖帽，使所含样本流入收集器下端。（步骤3）
将试剂盒置于干净平坦的台面上，同时打开滴样孔盖帽。（步骤4）
挤压收集器上端管壁，垂直滴加2滴无空气泡的唾液（约100ul）于加样孔（S）中。(步骤5)
等待紫红色条带的出现，3-5分钟时直接观察结果，10分钟后判定无效。

可替宁检测试剂盒

前列腺癌是男性常见恶性肿瘤，但目前还缺乏有效的诊断方法区分“高危害”与“非转移性惰性”（Indolent）前列腺癌。PTEN是前列腺癌中发生突变的肿瘤抑制基因，约有70%的转移性前列腺癌病人呈现PTEN缺失或PI3K/AKT信号通路异常激活；但是小鼠前列腺上皮细PTEN特异性敲除却不能形成高转移性前列腺癌，因此寻找及鉴定能够协同PTEN缺失促进前列腺癌转移的关键信号通路或因子，可以为临床的诊断和治疗提供新的靶点和思路。课题组发现，肝癌细胞通过分泌一种特定细胞因子吸引巨噬细胞成为自己的“帮凶”，从而存活下来,赵斌课题组建立了一种新型的小鼠活体肝细胞基因编辑体系，这一新型的体系可以“定向”让个别正常的肝细胞先行癌变，并精确模仿肝癌的发展进程。“绝大多数的癌症都是由个别正常的体细胞突变而来，新型技术揭示出，当*个细胞癌变时，肿瘤是怎样一步步发生发展的。”赵斌介绍。课题组发现，肝癌细胞通过分泌一种特定细胞因子吸引巨噬细胞成为自己的“帮凶”，从而存活下来。研究人员介绍，并巨噬细胞是人体内一种重要的免疫细胞，该细胞会定向识别吞噬病原体，但在单个体细胞初期癌变的阶段，巨噬细胞却能够抑制免疫细胞，肿瘤细胞从而成功逃过免疫监视，避免被清除。 “具有识别和对抗癌细胞功能的免疫细胞‘缴械投降’，是肿瘤细胞得以进一步发展的重要原因。在肝癌发生的起始阶段，课题组观察到了这种现象并找到了。一直以来，CB1结构成谜，但它却是治疗疼痛、炎症、肥胖症以及药物滥用的潜在药物靶点，不少相关药物的研究都绕不过它，甚至还有不少研发的药物因为缺乏CB1的结构信息，导致药物的专一性差而对人体产生副作用。CB1是人的中枢神经系统中表达量zui高的G蛋白偶联受体（GPCR）之一。并巨噬细胞是人体内一种重要的免疫细胞，该细胞会定向识别吞噬病原体，但在单个体细胞初期癌变的阶段，巨噬细胞却能够抑制免疫细胞，肿瘤细胞从而成功逃过免疫监视，避免被清除。

想了解更多的韩国SD产品及服务请扫描下方二维码：我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【公司名称】广州健仑生物科技有限公司
【】杨永汉

【】
【腾讯】
【公司地址】广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-3室

【企业文化宣传】

Prostate cancer is a common malignancy in men, but there is a lack of effective diagnostic methods to distinguish between "high-risk" and "non-metastatic" (Indolent) prostate cancer. PTEN is one of the most widespread tumor suppressor genes in prostate cancer. Approximay 70% of patients with metastatic prostate cancer have PTEN deletion or abnormal activation of PI3K / AKT signaling pathway. However, PTEN-specific knockout of mouse prostate epithelium can not form high Metastatic prostate cancer. Therefore, finding and identifying key signaling pathways or factors that can cooperate with PTEN deletion in promoting prostate cancer metastasis can provide new targets and ideas for clinical diagnosis and treatment. The research team found that liver cancer cells through the secretion of a specific cytokine to attract macrophages become their own "accomplice" to survive, Zhao Bin task force to establish a new mouse living hepatocyte gene editing system, this new System can be "targeted" for individual normal liver cells advance carcinogenesis, and accuray mimic the development of liver cancer. "The vast majority of cancers are caused by mutations in individual normal somatic cells, and newer technologies reveal how tumors develop step by step as the first cell becomes cancerous," said Zhao Bin. Task force found that liver cancer cells by secreting a specific cytokine to attract macrophages become their own "accomplice" and thus survive. The researchers introduced and macrophages is an important immune cells in the human body, the cells will be targeted to identify phagocytic pathogens, but in the initial stage of the somatic cells of an individual, macrophages can inhibit immune cells, tumor cells and thus successfully escape Immunization surveillance to avoid being cleared. "With the immune cells that recognize and fight against cancer cells," surrender "is an important reason for the further development of tumor cells, which was observed and found in the initial stage of liver carcinogenesis. However, it is a potential drug target for the treatment of pain, inflammation, obesity and drug abuse. Many related drug research has not been able to get around it. There are even many research and development of drugs because of the lack of CB1 structural information, Leading to poor specificity of the drug and side effects on the human body.CB1 is one of the highest expression of G protein-coupled receptors (GPCR) in human central nervous system and macrophages are an important immune cells in the human body, The cell directs the phagocytosis of pathogens, but during the initial stage of somatic cell myxogenesis, macrophages inhibit immune cells and tumor cells from escaping immune surveillance to avoid being cleared.