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美国US 违禁药物滥用五联卡

广州健仑生物科技有限公司

广州健仑长期供应各种违禁品检测试纸、违禁品检测卡、违禁品检测试剂盒、药筛试纸、药筛试剂盒等，包括进口和国产的不同品牌。

主营品牌：美国US、美国Alfa、美国NovaBios、美国Cortez、国产创仑等等。

主要用途：筛查违禁品滥用残留、麻醉类药物残留、兴奋类药物残留等等。

检测范围：吗啡、巴比妥、尼古丁、KET、mamp、MDMA、BZO、THC、MTD、BAR、MDMA、AMP、BUP、PCP、TCA、OXY、MET等等。

产品特点：可以根据需求自主订制多联卡。可以自由组合，从二联到十五联都可以订制。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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美国US 违禁药物滥用五联卡

尿液试纸、唾液试纸、尼古丁检测卡、烟碱检测卡、违违禁品三联检测卡、违禁品五联检测卡、违禁品十联检测卡、药筛试剂、违禁品滥用检测试纸、违禁品快速检测试剂盒

美国US多联检测杯简介：

美国US单卡产品简介：

【功能介绍】

可以检测尿液中是否含吗啡成分。从而定性判断被测者是否吸食了吗啡。 

【样品要求】

用一次性尿杯收集尿样，无需处理可直接检测。

【检验方法】

1、测试前先阅读使用说明书；

2、用干净尿杯取尿样；

3、从铝箔袋中取出检测卡，置于干净平坦的台面上，用吸管；垂直滴加2-3滴尿样到加样孔中；

4、3-5分钟读结果。为确保结果的准确性，请勿在5分钟后判读结果。

【结果解释】

1、阳性：在反应区内只出现一条红色质控线。

2、阴性：在反应区内出现质控线和反应线两条红线。

3、无效：在反应区内质控线未出现，需重新测试。

【注意事项】

1、检测卡在室温下一次性使用，不得重复使用；

2、检测卡从铝箔袋中取出后应在30分钟内尽快使用

3、3~5分钟内判定结果，10分钟后的结果无效

4、谨防检测卡受潮，检测卡受潮或铝箔袋破损后，检测卡不能使用

5、由于标本采集时存在差异，检测过程中可能出现质控线C和反应线T的颜色深浅或明暗不等，但只要可见，不管其颜色深浅或明暗均应视为出现。

美国US

基因型：supE44，hsdS20（rB-mB－），recA13，ara－14，proA2，lacY1，galK2，rpsL20，xyl-5，mtl-1，leuB6，thi-1
大多数疫苗中的脂质体的粒径都属于纳米级，但很少有深入研究脂质体粒径的大小与免疫反应之间的关系。一般来说，脂质体的粒径大于500nm，容易被单核巨噬细胞系统（mononuclear phagocytic system，MPS）吞噬，粒径为20-200nm之间容易被树突状细胞（DC）内吞（endocytosed）[129]。也就是说，较大的脂质体粒子更容易被MPS清除。
对于在皮肤上的局部免疫接种，粒径小于100nm的粒子能通过细胞间隙流进到淋巴结，并与淋巴结的DC细胞相互作用[130-133]。较大的脂质体（>500nm）通常被限制在注射部位，被皮肤的DC细胞或单核细胞内吞，难以移行到淋巴结[134]。中等大小的颗粒（100-500nm）能够主动或被动的移行到淋巴结。
有实验利用大鼠通过皮下注射方式研究脂质体粒径对其吸收和生物分布。脂质体是用卵磷脂（egg phosphatidylcholine，EPC）、卵磷脂酰甘油（egg phosphatidylglycerol）和胆固醇按10:1:4的比例制成。脂质体的粒径分别为40nm、70nm、170nm、400nm和大于1000nm。结果表明，淋巴吸收的程度与脂质体的大小呈负相关。40nm的脂质体迅速被淋巴系统吸收（52小时内被吸收了74%），而zui大的脂质体（大于1000nm）几乎在淋巴管检测不到[135]。
有人对基于biphosphanates的脂质体进行了深入研究[136]。脂质体的大小从80-650nm，这些脂质体中分别含有正电荷、负电荷和中性粒子。研究结果也表明，较大的脂质体容易被单核细胞和巨噬细胞吞噬。对大鼠和家兔静脉注射（intravenous）不同大小的脂质体，结果表明，较小的脂质体会降低单核细胞的活性。粒径小于80nm的脂质体在体内和体外都不具有活性，而大于190nm的脂质体能激活细胞因子活性。Mann等的研究表明，250nm脂质体能增强Th2反应，而1μm左右的脂质体能增强Th1反应，刺激产生高水平的IFN-γ和IgG2的抗体[137]。
有人对脂质体DNA的大小在组织中的定位进行了研究[138]。实验脂质体由EPC、DOPE和DOTAP组成，包裹着编码OVA的质粒DNA。脂质体的粒径为500nm或140nm。对小鼠皮下注射脂质体DNA，结果发现，较大的脂质体DNA粒子保留在注射部位的能力比小粒子强。大粒子脂质体DNA即使注射免疫3次后，仍然检测不到OVA特异的IgG抗体，而小粒子脂质体DNA注射第2次后即可检测到IgG抗体。zui后一次免疫三周后，分离脾细胞检测OVA特异性T细胞的百分比。大粒子脂质体DNA诱导OVA特异性CD8 + T细胞的量可忽略不计，小粒子诱导CD8 + T细胞的量显著增加，IFN-γ的量也显著增加。这项研究结果表明，小粒子脂质体作为DNA疫苗递送载体的效率更高。

美国US

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、食品安全、化妆品检测、药物滥用检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

想了解更多的产品及服务请扫描下方二维码：

【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

【】 
【腾讯  】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

Genotypes: supE44, hsdS20 (rB-mB-), recA13, ara-14, proA2, lacY1, galK2, rpsL20, xyl- 5, mtl- 1, leuB6, thi-1
Liposomes in most vaccines are nanoscale in size, but there is little insight into the relationship between the size of liposomes and the immune response. In general, liposomes are more than 500 nm in size and are easily phagocytosed by the mononuclear phagocytic system (MPS). Liposomes are readily engulfed by dendritic cells (DCs) between 20-200 nm in size endocytosed) [129]. That is, larger liposome particles are more easily cleared by MPS.
For topical immunization on the skin, particles <100 nm in size can flow into the lymph nodes through the intercellular space and interact with DC cells in the lymph nodes [130-133]. Larger liposomes (> 500 nm) are usually confined to the site of injection and are endocytosed by the skin's DC cells or monocytes, making it difficult to migrate to the lymph nodes [134]. Medium sized particles (100-500 nm) migrate actively or passively to lymph nodes.
Experiments using rats by subcutaneous injection of liposomes to study the size of its absorption and biodistribution. Liposomes are made with egg phosphatidylcholine (EPC), egg phosphatidylglycerol and cholesterol in a ratio of 10: 1: 4. The liposomes have particle sizes of 40 nm, 70 nm, 170 nm, 400 nm, and greater than 1000 nm, respectively. The results showed that the degree of lymphatic absorption and liposome size was negatively correlated. Liposomes at 40 nm were quickly absorbed by the lymphatic system (74% absorbed in 52 hours), whereas the largest liposomes (> 1000 nm) were almost undetectable in the lymphatic vessels [135].
Liposomes based on biphosphanates have been intensively studied [136]. Liposomes range in size from 80-650 nm, and these liposomes contain positive and negative charges and neutrals, respectively. The results also show that larger liposomes are easily phagocytosed by monocytes and macrophages. Liposomes of different sizes were intravenously administered to rats and rabbits and the results showed that smaller liposomes decreased monocyte activity. Liposomes with particle sizes less than 80 nm are inactive in vivo and in vitro whereas liposomes greater than 190 nm activate cytokine activity. Studies by Mann et al. Showed that 250 nm liposomes enhance the Th2 response and that about 1 μm liposomes enhance Th1 responses and stimulate high levels of IFN-γ and IgG2 antibodies [137].
The location of liposome DNA in tissues has been studied [138]. The experimental liposomes consisted of EPC, DOPE and DOTAP, encapsulating plasmid DNA encoding OVA. Liposomes have a particle size of 500 nm or 140 nm. Subcutaneous injection of liposomal DNA into mice resulted in the discovery that larger liposomal DNA particles retained the ability to inject at the injection site than small particles. Large particle liposomal DNA still failed to detect OVA-specific IgG antibodies after three immunizations, whereas IgG antibodies were detected after the second injection of small particle liposomal DNA. Three weeks after the last immunization, spleen cells were isolated for detection of the percentage of OVA-specific T cells. The amount of OVA-specific CD8 + T cells induced by large particle liposomal DNA was negligible, the amount of CD8 + T cells induced by small particles was significantly increased, and the amount of IFN-γ was also significantly increased. The results of this study show that small particle liposomes are more efficient as DNA vaccine delivery vectors.