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Panbio登革热抗原检测试剂

广州健仑生物科技有限公司

本公司为大家供应各种进口品牌登革热检测试剂盒，包括澳洲Panbio、美国NovaBios、美国CORTEZ等美国CDC品牌。主要包括胶体金、酶免、PCR等方法学。欢迎咨询

Panbio登革热抗原检测试剂

非洲工作用登革热试纸

热带国家旅游用登革热检测试纸

登革热IgM抗体、登革热IgG抗体、登革热NS1抗原、登革热早期检测试剂盒

登革热核酸检测试剂盒

Panbio公司简介:
1、1988年成立，2001年在澳大利亚证券交易所上市。
2、Panbio系关于虫媒感染性疾病及热带感染性疾病的专业供货商。
3、产品面向虫媒感染性疾病的检测，在国内疾控系统具有*的认知和认可度。
4、2010年销售800万检测试剂，为30多种疾病提供诊断。

Panbio登革热介绍：

1、登革热快速检测试剂(Dengue Duo Cassette R-DEN03D)
用于定性的快速检测人群血清、血浆或全血中登革病毒的IgM及IgG抗体。可在15分钟内检测结果。

2、登革IgM捕捉ELISA(Dengue IgM Capture ELISA E-DEN01M)
用于定性的检测人群血清中登革病毒的IgM抗体，用于临床实验室对具有持续发烧的登革热症状的病人的辅助诊断。

3、登革IgG捕捉ELISA(Dengo IgG Capture ELISA E-DEN02G)
用于定性检测血清中登革病毒(血清型1、2、3及4型)的IgG抗体。用于临床实验室对继发登革热感染的辅助诊断。

4、登革早期ELISA(Dengue Early ELISA E-DEN01P)
用于定性检测血清中登革病毒的NS1抗原(血清型1、2、3及4型)。用于临床实验室对有持续发烧的登革热症状病人的辅助性诊断。

5、登革IgG间接ELISA(Dengue IgG Indirect ELISA E-DEN01G)
用于定性检测血清中登革病毒(血清型1、2、3及4型)的IgG抗体，用于临床实验室对具有持续发烧的登革感染症状或接触史的患者的辅助性诊断。

6、登革IgM & IgG联检ELISA(Dengue Duo IgM & IgG Capture ELISA E-DEN01D)
用于定性检测血清中登革病毒的IgM和IgG抗体。可以区分原发感染与继发感染。

Dengue产品介绍

Panbio

登革热病是由登革热病毒引起，主要通过伊蚊叮咬传播的急性传染病。临床以高热、头痛、黄疸、蛋白尿、相对缓脉和出血等为主要表现。本病在非洲和南美洲的热带和亚热带呈地方性流行，亚洲尚无本病报告。由于登革热病的死亡率高及传染性强，已纳入世界卫生组织规定之检疫传染病之一。
病因
登革热病病毒属虫媒病毒B组披膜病毒科，病毒直径22～38纳米，呈球形，有包膜，含单股正链RNA。易被热、常用消毒剂、Panbio登革热、去氧胆酸钠等灭活，但在血中能于4℃保存1个月，在50%甘油中于0℃下可存活数月，于-70℃或冷冻干燥条件下可保持活力数年。zui初分离的登革热病毒Asibi株通过组织培养弱化成17D株，用以制备减毒活疫苗，预防效果良好。
临床表现
潜伏期3～6天。多数受染者症状较轻，可仅表现为发热、头痛、轻度蛋白尿等，持续数日即恢复。重型患者只发生在约15%的病例。病程经过可分为4期。
1.感染期
急起高热伴有寒战、剧烈头痛及全身痛，明显乏力、食欲不振、恶芯、呕吐、腹泻或便秘等。患者烦躁不安，结膜充血，面、颈潮红。心率与发热平行，以后转为相对心搏徐缓。本期持续约3天，此时病毒在血中达高滴度，成为蚊虫感染的来源。期末可有轻度黄疸、蛋白尿。
2.缓解期
发热部分或*消退，症状缓解，持续数小时至24小时。
3.中毒期
发热与症状复现，且更加重。此期毒血症消退，出现肝、肾、心血管功能损害以及出血症状。血清胆红素明显升高，凝血酶原时间延长，蛋白尿、少尿与氮质血症的程度和病情成正比。本期突出症状为严重的出血如齿龈出血、鼻出血、皮肤黏膜淤斑、胃肠道、尿道和子宫出血等。心脏常扩大，心搏徐缓，心音变弱，血压降低。常伴有脱水、酸中毒，严重者出现谵妄、昏迷、尿闭、顽固性呃逆、大量呕血、休克等。本期持续3～4天或2周。常在第7～10天发生死亡。
4.恢复期
体温下降至正常。症状和蛋白尿逐渐消失，但乏力可持续1～2周或更久。此期仍需密切观察心脏情况，个别病例可因心律不齐或心功能衰竭死亡。存活病例一般无后遗症。
实验室及其他检查
1.一般常规和生化检查
外周血白细胞总数正常或升高，但在本病早期中性粒细胞数常减少。血小板计数正常或减少。血清胆红素、ALT和AST升高，死亡病例更为明显。有黄疸的病例凝血酶原时间及部分凝血活酶时间延长。尿蛋白增多、血清尿素及肌酐升高。
2.病毒分离
采取病初3～4天内血标本接种小白鼠脑内或细胞培养可分离出病毒并用血清学方法进行鉴定。

Panbio

我司还提供其它进口或国产试剂盒：登革热、疟疾、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

想了解更多的Panbio产品及服务请扫描下方二维码：

【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

【】 
【腾讯  】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

references：

Dengue fever is caused by dengue virus, mainly through the mosquito bites spread of acute infectious diseases. Clinical to high fever, headache, jaundice, proteinuria, relative slow pulse and bleeding as the main performance. The disease in Africa and South America, tropical and subtropical was local epidemic, Asia, no disease reported. Due to the high mortality and contagious nature of dengue fever, it has been included in one of the quarantine infectious diseases prescribed by the World Health Organization.
Etiology
Dengue virus is a parasitic virus virus B group Phaffia virus family, the virus diameter of 22 to 38 nm, spherical, with a single strand of positive strand RNA. Easy to be hot, commonly used disinfectants, Panbio dengue fever, sodium deoxycholate and other inactivation, but in the blood can be stored at 4 ℃ for 1 month in 50% glycerol at 0 ℃ can survive for several months, at -70 ° C or freeze-drying conditions can be maintained for several years. The original isolated dengue virus Asibi strain was weighed into tissue 17D strain to prepare attenuated live vaccine, and the prevention effect was good.
Clinical manifestations
Incubation period of 3 to 6 days. Most of the infected people mild symptoms, can only show fever, headache, mild proteinuria, etc., for several days to recover. Severe patients only occur in about 15% of cases. The course of the disease can be divided into four periods.
Infection period
Acute high fever accompanied by chills, severe headache and body pain, obvious fatigue, loss of appetite, evil core, vomiting, diarrhea or constipation. Patients with irritability, conjunctival hyperemia, face, neck flushing. Heart rate and fever parallel, later to relatively slow heartbeat. This period lasts about 3 days, this time the virus in the blood of high titer, become the source of mosquito infection. At the end of the period may have mild jaundice, proteinuria.
2. Remission period
Fever partial or complete regression, symptom relief, lasted several hours to 24 hours.
3. poisoning period
Fever and symptoms recur, and more emphasis. This period of toxemia subsided, liver, kidney, cardiovascular damage and bleeding symptoms. Serum bilirubin was significantly increased, prothrombin time prolonged, proteinuria, oliguria and azotemia and the degree of disease is proportional to the disease. This period highlights the symptoms of severe bleeding such as gum bleeding, epistaxis, skin and mucous membrane eczema, gastrointestinal tract, urethra and uterine bleeding. The heart often expanded, heart beat slowly, heart sounds weak, lower blood pressure. Often accompanied by dehydration, acidosis, severe delirium, coma, urinary closure, intractable hiccups, a large number of hematemesis, shock and so on. This period lasts 3 to 4 days or 2 weeks. Often in the first 7 to 10 days of death.
4. recovery period
Body temperature dropped to normal. Symptoms and proteinuria gradually disappear, but the fatigue can last 1 to 2 weeks or longer. This period still need to closely observe the heart, individual cases may be due to arrhythmia or heart failure death. Survival cases are generally no sequelae.
Laboratory and other inspections
1. General routine and biochemical tests
Peripheral white blood cells in the normal or elevated, but in early childhood the number of neutrophils often reduced. Plaet counts are normal or reduced. Serum bilirubin, ALT and AST increased, more serious cases of death. The time of prothrombin time and partial thromboplastin prolongation in patients with jaundice. Increased urinary protein, serum urea and creatinine increased.
2. virus isolation
To take the first 3 to 4 days of the disease blood samples inoculated with the mouse brain or cell culture can be isolated from the virus and serological methods for identification.