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华瑞科研网-ELISA试剂盒
“Anti-CDO1抗体,半*双加氧酶1抗体科研“我公司拥有*的细胞服务技术,*的仪器设备和专业的ELISA检测试剂盒、生物索标记、荧光索标记、酶标记等,广泛用于多种分析研究与技术测定。咨询,我们将竭诚为你服务!
Anti-CDO1抗体,半*双加氧酶1抗体科研产品介绍:
CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
PathwayOrganosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.
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产品详情:
产品编号:HRK-5808R
产品规格: 0.1ml/0.2ml
产品别名:Cysteine Dioxygenase Type 1; CDO 1; CDO; CDO I; CDO1; CDO-1; CDOI; Cytosolic cysteine dioxygenase; CDO1_HUMAN
产品价格:询价(电询或客服)
产品用途:科研实验
贮 存: 贮存于-20℃.
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