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CD26抗体,Anti-CD26抗体

阅读:345发布时间:2014-12-13

CD26抗体,Anti-CD26抗体Background: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3

CD26抗体,Anti-CD26抗体别    名 ADCP2; DPPIV; Dipeptidyl peptidase 4; ADABP; ADCP 2; Adenosine deaminase complexing protein 2; CD 26; CD26; CD26 antigen 3; Dipeptidyl peptidase 4; Dipeptidyl peptidase iv; Dipeptidylpeptidase 4; Dipeptidylpeptidase IV; DPP 4; DPP IV; DPP4; Intestinal dipeptidyl peptidase; T cell activation antigen CD26; TP 103; TP103

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